BackgroundThe safety of sleeping pills has increased dramatically during the last 100 years, from barbiturates to bensodiazepines to modern day so-called Z-drugs.MethodsThe circumstances of prescribing sleeping pills in the early 20th century are illustrated by summarizing the main storyline of a novel by Swedish writer Vilhelm Moberg. This is followed by a thought experiment and a theoretical discussion.ResultsIn his 1937 novel Sömnlös (Swedish for sleepless) Vilhelm Moberg portrayed existential and relational distress in relation to insomnia. In a thought (...) experiment, past progresses in sleeping pills safety are projected into the future. Thereby, it is claimed that important issues in the area of philosophy of medicine come to the fore. This leads to a theoretical discussion about broader questions concerning the role of the physician, the goals of medicine (as described by Lennart Nordenfelt), the concept of pharmaceuticalisation (as described notably by sociologist of sleep Simon J. Williams and co-workers), and health enhancement (c.f. Carl Elliott and the alleged wish to be better than well).ConclusionInsomnia is a prism through which important philosophical and sociological questions related to the practice of medicine can be asked. (shrink)

With In Search of Mechanisms, Carl F. Craver and Lindley Darden offer both a descriptive and an instructional account of how biologists discover mechanisms. Drawing on examples from across the life sciences and through the centuries, Craver and Darden compile an impressive toolbox of strategies that biologists have used and will use again to reveal the mechanisms that produce, underlie, or maintain the phenomena characteristic of living things. They discuss the questions that figure in the search for mechanisms, characterizing (...) the experimental, observational, and conceptual considerations used to answer them, all the while providing examples from the history of biology to highlight the kinds of evidence and reasoning strategies employed to assess mechanisms. At a deeper level, Craver and Darden pose a systematic view of what biology is, of how biology makes progress, of how biological discoveries are and might be made, and of why knowledge of biological mechanisms is important for the future of the human species. (shrink)

In the 21st century, Carl Gustav Jung (1875-1961) remains one of the key figures in the field of analytical psychology - and Psychological Types, or The Psychology of Individuation, published in 1921, is one of his most influential works. It was written during the decade after the publication of Psychology of the Unconscious (1912), which effectively ended his friendship and collaboration with Sigmund Freud. Whereas the earlier work had clearly marked Jung's psychoanalytical divergence from Freud it is the Psychology (...) of Types that fully clarifies and presents the nature, quality and characteristics of his analytical psychology. The work, which was in part a consequence of his need to reconcile the competing theories of Freud, whom he regarded as extraverted, and Alfred Adler, whom he saw as introverted, develops his concept of descriptive categories for understanding the human mind in terms of the two essential attitude types: introversion and extraversion. These basic attitudes operate in tandem with four principal interacting functions of consciousness which Jung identifies as sensation and intuition, which are functions of perception, and thinking and feeling, which are functions of judgment. The eight resulting psychological types are then explored, described, identified, characterised and explained in considerable detail, with a soaring range of examples drawn from the whole of human history, culture and experience. In his efforts to explore and illuminate the nature of the unconscious mind and indeed the collective unconscious, he investigates the problems posed by the differing psychological types and how these have manifested from classical and medieval times to the 20th century. His observations range from Aristotle, Socrates and Plato to Tertullian and Origen, and from Abélard and Master Eckhart to Martin Luther and the problem of transubstantiation. Jung takes the listener on an odyssey of human thinking. He considers the problem of types in the works of Schiller and Goethe, and Spitteler and his treatment of the Prometheus myth. He contrasts idealism and realism, the Apollonian and the Dionysian in Nietzsche, and explores a host of philosophical and religious sources from the Bible to Taoism to Brahminism. He considers the nature of the reconciling symbol in Spitteler before analysing the nature of types in modern philosophy, aesthetics and biography, giving detailed consideration to William James' characteristic pairs of opposites and Furneaux Jordan's 'character sketch of the emotional types'. Jung goes on to fully identify and describe the characteristic differences between the extraverted and introverted types and provides an extensive chapter on definitions to fully clarify the meaning of the language he employs and make his meaning more accessible. Authoritatively read by Martyn Swain for Ukemi Audiobooks, Psychological Types is an inexhaustible treasure chest of ideas and creative inspiration worth listening to time and time again. (shrink)

In this paper I argue against one variety of contextualism about aesthetic predicates such as “beautiful.” Contextualist analyses of these and other predicates have been subject to several challenges surrounding disagreement. Focusing on one kind of contextualism— individualized indexical contextualism —I unpack these various challenges and consider the responses available to the contextualist. The three responses I consider are as follows: giving an alternative analysis of the concept of disagreement ; claiming that speakers suffer from semantic blindness; and claiming that (...) attributions of beauty carry presuppositions of commonality. I will argue that none of the available strategies gives a response which both satisfactorily explains all of the disagreement -data and is plausible independent of significant evidence in favor of contextualism. I conclude that individualized indexical contextualism about the aesthetic is untenable, although this does not rule out alternative contextualist approaches to the aesthetic. (shrink)

This collection of articles and associated discussion papers focuses on a problem that has attracted increasing attention from linguists and psychologists throughout the world during the past several years. Reduced to essentials, the problem is that of discovering the character of the mental capacities that make it possible for human beings to attain knowledge of their language on the basis of fragmentary and haphazard early linguistic experience. A fundamental assumption running through all of these contributions is that people possess strong (...) innate predispositions that are critical for success in this task. (shrink)

"This book became a landmark, set up on the spot where two ways divided. Because of its imperfections and its incompleteness it laid down the program to be followed for the next few decades of my life." Thus wrote C. G. Jung about his most famous and influential work, the one that marked the beginning of his divergence from the psychoanalytic school of Freud. In this book Jung explores the fantasy system of Frank Miller, the young American woman whose account (...) of her poetic and vivid mental images helped lead him to his redefinition of libido while encouraging his explorations in mythology. Published in 1912 as Wandlungen und Symbole der Libido, this is a key text for the study of the formation of Jung's ideas and for understanding his personal and psychological condition during this crucial time. Miller's fantasies, with their mythological implications, supported Jung's notion that libido is not primarily sexual energy, as Freud had described it, but rather psychic energy in general, which springs from the unconscious and appears in consciousness as symbols. Jung shows how libido organizes itself as a metaphorical "hero," who first battles for deliverance from the "mother," the symbol of the unconscious, in order to become conscious, then returns to the unconscious for renewal. Jung's analytical commentary on these fantasies is a complex study of symbolic parallels derived from mythology, religion, ethnology, art, literature, and psychiatry, and foreshadows his fundamental concept of the collective unconscious and its contents, the archetypes. (shrink)

Network analysis is increasingly used to discover and represent the organization of complex systems. Focusing on examples from neuroscience in particular, I argue that whether network models explain, how they explain, and how much they explain cannot be answered for network models generally but must be answered by specifying an explanandum, by addressing how the model is applied to the system, and by specifying which kinds of relations count as explanatory.

The design argument for the existence of God took a probabilistic turn in the 17 th and 18 th centuries. Earlier versions, such as Thomas Aquinas' 5 th way, usually embraced the premise that goal-directed systems (things that "act for an end" or have a function) must have been created by an intelligent designer. This idea – which we might express by the slogan "no design without a designer" – survived into the 17 th and 18 th centuries, 1 and (...) it is with us still in the writings of many creationists. The new version of the argument, inspired by the emerging mathematical theory of probability, removed the premise of necessity. It begins with the thought that goal-directed systems might have arisen by intelligent design or by chance; the problem is to discern which hypothesis is more plausible. With the epistemic concept of plausibility characterized in terms of the mathematical concept of probability, the design argument was given a new direction. The new probabilistic perspective did not extinguish the older idea of "no design without a designer." The two conflicting approaches coexisted, often with less than perfect clarity about their fundamental difference. At the same time, the details of how the probabilistic perspective ought to be articulated were slow in emerging. These characteristics of uneven development are exemplified in a debate that took place in the 18 th century among three probabilists – John Arbuthnot, Nicholas Bernoulli, and Abraham DeMoivre – on the proper explanation of human sex ratio. Arbuthnot proposed a probabilistic version of the design argument, claiming that it is intelligent design, not chance, that provides the better explanation of why slightly more boys than girls are born each year. Bernoulli rejected Arbuthnot's argument. DeMoivre defended Arbuthnot against Bernoulli's criticisms. The problem of explaining sex ratio, both in human populations and in the rest of nature, experienced another transformation after 1859 --it became a problem for the theory of evolution by natural selection. Darwin (1871) addressed the question in the first edition of The Descent of Man but withdrew his suggestion in the second (Darwin 1874). Carl Düsing (1884) provided a mathematical model that moved beyond the explanation Darwin offered. Fisher (1930) added the new idea of parental expenditure. Williams (1966) argued that the sex ratios found in nature provide the opportunity to test hypotheses of group selection against hypotheses of individual selection. Hamilton (1967) constructed a model that generalizes Fisher's approach and represents the effects of both group and individual selection. The theory of natural selection gradually developed the ability to predict sex ratios, not just explain them post hoc. (shrink)

Despite all the attention to Big Data and the claims that it represents a “paradigm shift” in science, we lack understanding about what are the qualities of Big Data that may contribute to this revolutionary impact. In this paper, we look beyond the quantitative aspects of Big Data and examine it from a sociotechnical perspective. We argue that a key factor that distinguishes “Big Data” from “lots of data” lies in changes to the traditional, well-established “control zones” that facilitated clear (...) provenance of scientific data, thereby ensuring data integrity and providing the foundation for credible science. The breakdown of these control zones is a consequence of the manner in which our network technology and culture enable and encourage open, anonymous sharing of information, participation regardless of expertise, and collaboration across geographic, disciplinary, and institutional barriers. We are left with the conundrum—how to reap the benefits of Big Data while re-creating a trust fabric and an accountable chain of responsibility that make credible science possible. (shrink)

Carl Hausman presents here a sustained and systematic examination of the problems of constructing a framework for understanding the concept of creativity. His discussion is unique in focusing systematically on problems of understanding creativity, examining our assumptions about what we take to be creative, and the possibility of seeing how creativity fits into a world that we expect to behave in rational patterns. In a careful examination of this complex phenomena, Hausman suggests a way of approaching creativity in terms (...) of a novel theory of metaphor. (shrink)

I argue that Sellars’s distinction between signifying and picturing should be taken seriously by philosophers of mind, language, and cognition. I begin with interpretations of key Sellarsian texts in order to show that picturing is best understood as a theory of non-linguistic cognitive representations through which animals navigate their environments. This is distinct from the kind of discursive cognition that Sellars called ‘signifying’ and which is best understood in terms of socio-linguistic inferences. I argue that picturing is required because reflection (...) on signifying cannot adequately explain our need for cognitive friction. I then show how the idea of picturing is further developed by Paul Churchland, Ruth Garrett Millikan, and Huw Price. I finally turn to predictive processing as a theory of cognitive representation, and in particular Andy Clark’s ‘radical predictive processing’, to further characterize picturing. However, doing so has the cost of pushing picturing and signifying further apart than Sellars intended. (shrink)

Hodgkin and Huxley’s model of the action potential is an apparent dream case of covering‐law explanation in biology. The model includes laws of physics and chemistry that, coupled with details about antecedent and background conditions, can be used to derive features of the action potential. Hodgkin and Huxley insist that their model is not an explanation. This suggests either that subsuming a phenomenon under physical laws is insufficient to explain it or that Hodgkin and Huxley were wrong. I defend Hodgkin (...) and Huxley against Weber’s heteronomy thesis and argue that explanations are descriptions of mechanisms. †To contact the author, please write to: Department of Philosophy, Philosophy‐Neuroscience‐Psychology Program, Washington University in St. Louis, One Brookings Drive, Wilson Hall, St. Louis, MO 63130; e‐mail: [email protected]. (shrink)

This paper addresses the question of why democracy is desirable in terms of a relational theory of democracy. The theory draws on concepts from Aristotelian, critical realist, and psychoanalytic th...

A world awash in little understood chemicals tragically harms adults and children alike. Laws keep health agencies in the dark about toxicants, slow, well motivated research hampers protections, and strenuous vested opposition exacerbates the harm. How science is used in the tort law can facilitate or frustrate redress of harm. This book recommends better approaches.

Feyerabend claims that what is perceived depends upon what is believed ; and he maintains that among really efficient alternative theories "each theory will possess its own experience, and there will be no overlap between these experiences". According to Feyerabend "scientific theories are ways of looking at the world; and their adoption affects our general beliefs and expectations, and thereby also our experiences...". Toulmin, Hanson, and Kuhn concur with this view. Toulmin claims that men who accept different "ideals" and "paradigms" (...) will see different phenomena. He thinks theories not only give significance to facts, but also determine what facts are for us at all. Like Feyerabend, Toulmin asserts that "we see the world through" our fundamental concepts of science "to such an extent that we forget what it would look like without them". Indeed, both Feyerabend and Toulmin would have previous thinkers "live in an observational world very different from our own". Kuhn expresses quite similar views. He feels that. (shrink)

Carl Olson is Professor of Religious Studies at Allegheny College in Pennsylvania. His previous books include The Indian Renouncer and Postmodern Poison: A Cross-Cultural Encounter and The Theology and Philosophy of Eliade: A Search for the Centre.

This chapter contains sections titled: Introduction The Once Received View (ORV) Criticisms of the ORV The “Model Model” of Scientific Theories Mechanisms: Investigating Nonformal Patterns in Scientific Theories Conclusion.

Long-Term Potentiation (LTP) is a kind of synaptic plasticity that many contemporary neuroscientists believe is a component in mechanisms of memory. This essay describes the discovery of LTP and the development of the LTP research program. The story begins in the 1950's with the discovery of synaptic plasticity in the hippocampus (a medial temporal lobe structure now associated with memory), and it ends in 1973 with the publication of three papers sketching the future course of the LTP research program. The (...) making of LTP was a protracted affair. Hippocampal synaptic plasticity was initially encountered as an experimental tool, then reported as a curiosity, and finally included in the ontic store of the neurosciences. Early researchers were not investigating the hippocampus in search of a memory mechanism; rather, they saw the hippocampus as a useful experimental model or as a structure implicated in the etiology of epilepsy. The link between hippocampal synaptic plasticity and learning or memory was a separate conceptual achievement. That link was formulated in at least three different ways at different times: reductively (claiming that plasticity is identical to learning), analogically (claiming that plasticity is an example or model of learning), and mechanistically (claiming that plasticity is a component in learning or memory mechanisms). The hypothesized link with learning or memory, coupled with developments in experimental techniques and preparations, shaped how researchers understood LTP itself. By 1973, the mechanistic formulation of the link between LTP and memory provided an abstract framework around which findings from multiple perspectives could be integrated into a multifield research program. (shrink)

The clash between religious freedom and equality for lesbians and gay men has become a controversial legal issue in the United Kingdom. Increasingly, claims are made that compliance with anti-discrimination norms impacts upon conscientious, faith-based objectors to same-sex sexual acts. This article explores this issue and draws insights from North American case law, where this question has been considered in the context of competing constitutional rights. It raises far-reaching issues concerning the distinction between belief and practice, as well as the (...) role of identity in the public sphere. The author advocates that courts and tribunals should adopt a fact-specific approach which is sensitive to the rights in a particular context, and which focuses upon the values of accommodation, tolerance and mutual respect. (shrink)

No statue raised in a public place should stand there indefinitely. Any such monument should have a set date when it is due to be replaced. I make three arguments to support this principle of non-permanence for public commemorative art. First, the opportunity cost of permanent statues is too high. States have a duty, grounded in their need for legitimacy, to support and cultivate democratic values. Public art is a powerful tool that is being drastically underemployed because existing statues are (...) already taking up so many prominent sites. Second, permanence undermines stability by unnecessarily raising the stakes of change and so exacerbating predictable tensions between social groups who ought to be able to respect one another as honourable civic partners. My proposal reduces the significance of replacing a monument by making removals a commonplace event. Third, we ought to do away with permanent statues as a means of increasing democratic control for both current and future generations over public spaces. Each generation inherits a more cluttered civic landscape which makes it progressively more difficult to shape it in accordance with their needs, preferences, and cultural vocabulary. Taken together, these arguments tip the balance of reasons decisively against the status quo. (shrink)

This book offers a bold new theoretical understanding of the current ecological crisis via the Frankfurt School. Focusing on key notions of dialectics, natural history, and materialism, a critical theory of nature is outlined in favor of a more traditional Marxist theory of nature, albeit one which still builds on Marxist concepts to confirm humanity's centrality in manufacturing environmental misery. Pre-eminent thinkers including Georg Lukács, Ernst Bloch, and Theodor Adorno are highlighted for their potential to diagnose the interpenetration of capitalism (...) and nature in a way that neither absolutizes nor obliterates the boundary between the social and natural. (shrink)

Bioethics is now taken seriously. Is there a danger of its being taken in or taken over? Might it be influenced in other ways, less visible and less easily avoided? As private corporations and bioethicists build relationships with each other, bioethicists must ask themselves about the opportunities, the constraints, and the subtle shifts in attitude and focus that such ties might create.

Some people change dramatically over time, and often those changes result partly from what they have chosen to do for a living. Drawing on the work of Richard Sennett and Sandeep Jauhar, I explore how practicing in a market-driven medical system can corrupt the character of doctors.

ABSTRACTThis essay argues that in spite of the powerful arguments by Kolodny and Broome there is a reason to be rational. The suggested reason to be rational is that if an agent complies with ratio...

Ernst Mayr's typological/population distinction is a conceptual thread that runs throughout much of his work in systematics, evolutionary biology, and the history and philosophy of biology. Mayr himself claims that typological thinking originated in the philosophy of Plato and that population thinking was first introduced by Charles Darwin and field naturalists. A more proximate origin of the typological/population thinking, however, is found in Mayr's own work on species. This paper traces the antecedents of the typological/population distinction by detailing Mayr's changing (...) views of species between 1942 and 1955. During this period, Mayr struggles to refine the biological species concept in the face of tensions that exist between studying species locally and studying them as geographically distributed collections of variable populations. The typological/population distinction is first formulated in 1955, when Mayr generalizes from the type concept versus the population concept in taxonomy to typological versus population thinking in biology more generally. Mayr's appeal to the more general distinction between typological and population thinking coincides with the waning status of natural history and evolutionary biology that occurs in the early 1950s and the distinction plays an important role in Mayr's efforts to legitimate the natural historical sciences. (shrink)

We consider modifications to the standard David Lewis signaling game and relax a number of unrealistic implicit assumptions that are often built into the framework. In particular, we motivate and explore various asymmetries that exist between the sender and receiver roles. We find that endowing receivers with a more realistic set of responses significantly decreases the likelihood of signaling, while allowing for unequal selection pressure often has the opposite effect. We argue that the results of this article can also help (...) make sense of a well-known evolutionary puzzle regarding the absence of an evolutionary arms race between sender and receiver in conflict-of-interest signaling games. (shrink)